4. Big Trouble (2002)
A lot of people haven't heard of Tim Allen's other neo-noir comedy Big Trouble, and that's not because it's a bad movie, which it isn't. The reason the Barry Sonnenfeld-directed comedy with a cast that includes Rene Russo, Stanley Tucci, Ben Foster, Zooey Deschanel, Tom Sizemore, and so many others has been lost to time is the fact that it had to abandon its original release date due to the attacks on September 11, 2001. Big Trouble features a comedic scene in which a nuclear device is snuck onto a plane, something that wouldn't fly in the weeks following the devastating attacks. Despite this, the story about how a mysterious suitcase brings a group of broken people together (and a lot of dicey situations) remains one of the most clever and hilarious comedies of the era. Just look out for those toads.